Proton Pump Inhibitors Should be Used with Caution in Critically Ill Patients to Prevent the Risk of Clostridium difficile Infection
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چکیده
منابع مشابه
Proton Pump Inhibitors Should be Used with Caution in Critically Ill Patients to Prevent the Risk of Clostridium difficile Infection
The incidence and severity of Clostridium difficile infection (CDI), which is the most important cause of nosocomial diarrhea , have increased globally. 1-4 In North America and Europe, CDI has been well established for decades, becoming a particular issue after 2000. 1 A recent nationwide study conducted in South Korea involving 17 hospitals indicated that the incidence of CDI is significantly...
متن کاملProton pump inhibitors increase the risk for hospital-acquired Clostridium difficile infection in critically ill patients
INTRODUCTION Proton pump inhibitors (PPI) have been linked to Clostridium difficile infection (CDI) but there are few data specific to ICU patients. We evaluated duration of PPI exposure as a potential risk factor for hospital-acquired CDI in the ICU. METHODS This retrospective, case-control study was conducted using the Multiparameter Intelligent Monitoring in Intensive Care II database, a l...
متن کاملProton pump inhibitors and risk for Clostridium difficile associated diarrhea.
Increased incidence of Clostridium difficile infection (CDI) among in-patients is associated with significant increased mortality, morbidity, and stay in the hospitals. This has occurred despite heightened awareness of the risks of broad-spectrum antibiotics, overall reduction in antibiotic use and increased focus on hospital hygiene. So though the main risk factor for CDI is use of broad-spect...
متن کاملShould selective digestive decontamination be used in critically ill patients?
Healthcare associated infection represents a major burden for critically ill patients; a recent point prevalence survey by the Health Protection Agency observed that 23.4% of patients in intensive care units had evidence of a healthcare associated infection.Ventilator associated pneumonia remains the leading cause of nosocomial infection in this population, and, although recent estimates of att...
متن کاملProton pump inhibitors therapy and risk of Clostridium difficile infection: Systematic review and meta-analysis
AIM To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs) therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a systematic search of MEDLINE/PubMed and seven other databases through January 1990 to March 2017 for published studies that evaluated the association between PPIs and CDI. Adult case-control and cohort studies providing infor...
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ژورنال
عنوان ژورنال: Gut and Liver
سال: 2016
ISSN: 1976-2283,2005-1212
DOI: 10.5009/gnl16216